The Caspase-3 Monoclonal Antibody (Clone 31A1067) from Cayman Chemical is a Mouse Monoclonal antibody. The Caspase-3 Monoclonal Antibody (Clone 31A1067) has been validated for the following applications: Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot.
Description
Antigen: recombinant full-length human caspase-3
• Host: mouse, clone 31A1067
• Isotype: IgG1κ
• Cross Reactivity: (+) human, mouse, and rat caspase-3
• Application(s): IHC (frozen and paraffin-embedded sections) and WB
• Caspase-3 cleaves the death substrate PARP to a specific 85 kDa form observed during apoptosis and is inhibitable by the CrmA protein. Other caspase-3 substrates include DNA-PK, actin, GAS2, procaspase-6, etc